Tadalafil Femalefil are two different medications used for different purposes. This is a well-known medication used primarily to treat erectile dysfunction (ED) in men. It works by increasing blood flow to the penis, helping to achieve and maintain an erection. Tadalafil is also used to treat symptoms of benign prostatic hyperplasia (BPH) and, in some cases, pulmonary arterial hypertension (PAH).